Although most physicians will agree that Biopuncture is probably much safer than cortisone injections and surgery, they still have doubts whether these ultra-low doses have any effect other than placebo. However, clinical observational studies have illustrated that products like Traumeel and Zeel do show clinical effects. Although these studies may show a lot of bias, the clinical findings are interesting enough to further examine the potential benefits of using these products, and how one can further develop the potential benefits of these local injections. Large multi-center studies with control subjects comparing each treatment type are needed to further improve the Biopuncture protocols.
It is obvious that biotherapeutics are less powerful than anti-inflammatory drugs and corticosteroids. Nevertheless, physicians are often surprised how good the clinical results can be -- both in short-term as well as long-term results. Most biopuncturists confirm that the long term results are even better than with cortisone injections. But such information is anecdotal. Large observational studies are crucial to confirm such statements. However, to achieve these clinical results, the right strategy and a correct injection technique is crucial.
The fact that medications like Traumeel only contain ultra-low doses does not mean that it produces no therapeutic effect at all. Even local application of Traumeel ampoules -- without injecting them -- is effective in the treatment of, e.g., stomatitis. This has been illustrated in a randomized, controlled double-blind study.
Recent research confirmed that even Traumeel cream application -- without injecting it -- is effective in tendinopathy. In a randomized trial with athletes the clinical affect of Traumeel ointment was found to be similar to diclofenac ointment (and both were better than placebo) in the treatment of tendinous pain.
But when ultra-low doses such as Traumeel are administered as local injections, they have even more effect. The medications acquire an extra dimension comparable to a turbo effect. These mechanisms related to the injection are extra effects that cannot be achieved by giving the same medications orally. A lot of physicians are realizing that there is a huge difference between giving, e.g., Traumeel injections in the area compared to, e.g., prescribing Traumeel tablets.
Walach H. The Efficacy Paradox in Randomized Controlled Trials of CAM and Elsewhere: Beware of the Placebo Trap, J Altern Complement Med 2001 (Jun); 7 (3): 213–218
Singer, SR., Amit-Kohn, M., Weiss, W., Rosenblum, J., Lukasiewicz, E., Itzchaki, M., Oberbaum, M. Post-operative pain control with Traumeel S after hallux valgus repair: a pilot study; Focus Altern Complement Ther. Vol.10: 50 (Abstract) (2005)